In order to take over a block, you must first Ransack it. During a Ransack, you must send Characters from your crew to create havoc on a block, eventually revealing the Boss of that block.

Depending on the block, there can be multiple Ransacks phases required to reveal the Boss.

To start a Ransack, characters from your crew must be assigned to it. The time needed to complete Ransacks vary depending on the block/district, and can always be skipped by spending Gold.